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Glutathione levels can be depleted by stress, poor nutrition, toxins, and illness, which is why supplementation through IV therapy can be especially beneficial

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Although brain infarction volume reduction did not reach statistical significance, motor performance in the rotarod test significantly recovered in DSIP-treated animals compared to vehicle controls — confirming a functionally relevant neuroprotective effect at the behavioural level and establishing intranasal delivery as a viable route for CNS DSIP research